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Dating of endometrium

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About

Endometrial dating in the conception cycle.

Page views in Accessed January 27th, Diagrams Phases Proliferative phase: Early proliferative endometrium Mid proliferative days 8 - Mid proliferative endometrium and Ki67 staining Late proliferative days 11 - Day 10 - 12 endometrium shows glands that are more tortuous and crowded; intraglandular nuclear pseudo- stratification and mitotic activity are more prominent see inset and the stroma is edematous and mitotically active Ovulation: Traditionally assumed to be 14 days, but may vary Progesterone secretion inhibits endometrial proliferative activity and induces secretory activity Note: Contributed by Andrey Bychkov, M. Day 17 endometrium, with reduced Ki67 staining Day

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Its cyclic structural changes mirror changes in metabolic functions, and both are regulated by ovarian estradiol and progesterone. Because of this interplay of structure, function, and ovarian hormonal stimuli, the endometrium is considered one of the most sensitive indicators of the hypothalamic-pituitary-ovarian hormonal axis. As a result, morphologic evaluation of the endometrium is used in diagnostic evaluation of infertile patients to determine whether ovulation is occurring Fig. Schematic representation of steroid hormone-morphologic interactions during the endometrial cycle. Estradiol promotes endometrial proliferation, whereas after ovulation, progesterone converts estradiol-primed endometrium into secretory tissue.

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Endometrial dating in the conception cycle. To investigate endometrial dating during the conception cycle.

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Dating the endometrial biopsy.

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